杨小枫研究员

研究简介
应用神经电生理学技术(离体和在体多种神经电生理记录技术)结合多组学技术(连接组学、遗传组学、转录组学、蛋白组学、代谢组学及肠道菌群组学)研究中枢神经环路形成机制。神经环路在神经系统及呼吸系统疾病发病机制中的作用,尤其是慢性咳嗽、慢阻肺、睡眠呼吸窘迫综合征及癫痫的疾病。同时重点从事基于AI技术的神经网络监控及神经调控疗法在上述疾病中的临床转化研究。
 
荣誉奖励
1. 科技部“一带一路”外国专家
2. 珠三角自主创新示范区9市和揭阳中德金属生态城外籍高层次人才
 
代表性成果
1.Liu X, Li Y, Li X, Chen S, Sui L, Su Z, Cheng L, Zhao K, Yang M, Lai H, Xing Y, Gui Y, Wang J, Yang X*, Zhou L*. (2023) Scalp ripple rates for rapid epilepsy differentiation and seizure activity assessment: Applicability and influential factors. Epilepsia. 2023 Mar 16. doi: 10.1111/epi.17587. Epub ahead of print. PMID: 36928628.
 
2.Liu R, Xing Y, Zhang H, Wang J, Lai H, Cheng L, Li D, Yu T, Yan X, Xu C, Piao Y, Zeng L, Loh HH, Zhang G and Yang X* (2022) Imbalance between the function of Na+-K+-2Cl and K+-Cl impairs Cl− homeostasis in human focal cortical dysplasia. Front. Mol. Neurosci. 15:954167. doi:10.3389/fnmol.2022. 954167
 
3.Li X, Zhang H, Lai H, Wang J, Wang W, Yang X*. High-Frequency Oscillations and Epileptogenic Network. Current Neuropharmacology. 2021;Sep 8.doi: 10.2174/ 1570159X19666210908165641. Cheng L, Xing X, Zhang H, Liu R, Lai H, Piao Y, Wang W, Yan X, Li X, Wang J, Li D, Loh H.H, Yu T, Zhang G,* Yang X.* Mechanistic analysis ofMicro-Neurocircuits underlying the epileptogenic zone in focal cortical dysplasia Patients. Cerebral Cortex. 2021; Oct 19;bhab350. doi: 10.1093/cercor/bhab350.
 
4.Wang W, li H, Yan J, Zhang H, Li X, Zheng S, Wang J, Xing Y, Cheng L, Li D, Lai H, Qu J, Loh HH , Fang F*, and Yang X* . Automatic detection of interictal ripples in scalp EEG to evaluate the effect and prognosis of ACTH therapy in patients with infantile spasms. Epilepsia 2021;Sep62(9):2240-2251.
 
5.Wang J, Jing B, Liu R, Li D, Wang W, Wang J, Lei J, Xing Y, Yan J, Loh H. H, Lu G, Yang, X*. Characterizing the seizure onset zone and network using EEG-fMRI in a rat seizure model. Neuroimage, 2021;Aug 15;237:118133.  Li X, Yu T, Ren Z, Wang X, Yan J, Chen X, Yan X, Wang W, Xing Y, Zhang X, Zhang G* and Yang X*. Localization of the Epileptogenic Zone by Multimodal Neuroimaging and High-frequency Oscillation. Front Hum Neurosci, 2021; Jun 8;15:677840. doi: 10.3389/fnhum.2021.677840. 
 
6.“一种头皮脑电高频振荡自动检测用电极贴”,中国,ZL 2021 2 1087313.7,2021-12-28,第一。
 
7.“一种脑电信号处理方法、装置以及计算机可读存储介质”,中国,ZL 2021 1 0857473.3,2022-07-29,第一。
 
8.“一种头皮脑电高频振荡自动检测方法”,中国,ZL 2021 1 0539870.6 ,2023-10-20,第一。