孟舒研究员
研究简介
长期致力于成纤维细胞转分化、血管再生机制及RNA therapy在心血管疾病的研究和治疗。在该研究领域共发表学术论文论著40 余篇，累计影响因子＞400,代表作发表在Circulation, Nature Communication，Circulation Research, ATVB等心血管专业核心期刊，主持参与NHLBI及AHA等多项基金$260万，现为广州国家实验室基础研究部研究员。主持国自然面上项目。
代表性成果
1. Liu Q, Wang Y, Zhang T, Fang J, Meng S. 2023. Circular RNAs in vascular diseases. Frontiers in Cardiovascular Medicine.
2. Lv J, Meng S, Gu Q, Zheng R, Gao X, Kim JD, Chen M, Xia B, Zuo Y, Zhu S, Zhao D, Li Y, Wang G, Wang X, Meng Q, Cao Q, Cooke JP, Fang L, Chen K and Zhang L. 2023. Epigenetic landscape reveals MECOM as an endothelial lineage regulator. Nature Communications. 14(1):2390
3. Meng S, Lv J, Chanda P, Owusu I, Chen K, Cooke JP. 2020. A Reservoir of Fibroblasts Promotes Recovery from Limb Ischemia. Circulation. 142:1647-1662.
4. Chanda P, Meng S, Lee J, Leung H, Chen K, Cooke JP. 2019. Nuclear S-nitrosylation defines an optimal zone for inducing pluripotency. Circulation. 140(13):1081-1099
5. Meng S, Chanda P, Thandavarayan RA, Cooke JP. 2018. Transflammation: How Innate Immune Activation and Free Radicals Drive Nuclear Reprogramming. Antioxidants & Redox Signaling. 29:205-218
6. Meng S, Gu Q, Yang X, Lv J, Owusu I, Matrone G, Chen KF, Cooke JP, Fang L. 2018. TBX20 regulates angiogenesis through the PROK2-PROK1R pathway. Circulation. 138:913-928
7. Meng S, Zhou G, Gu Q, Chanda PK, Ospino F, Cooke JP. 2016. Transdifferentiation requires iNOS activation: Role of ring1a s-nitrosylation. Circulation research. 119(9):e129-e38
8. Meng S, Matrone G, Lv J, Chen K, Wong WT, Cooke JP. 2016. LIM Domain Only 2 Regulates Endothelial Proliferation, Angiogenesis, and Tissue Regeneration. Journal of American Heart Association. 5(10)：e004117
9. Matrone G, Meng S, Gu Q, Lv J, Fang L, Chen K, Cooke JP. 2017. Lmo2 (lim-domain-only 2) modulates sphk1 (sphingosine kinase) and promotes endothelial cell migration. Arteriosclerosis, Thrombosis, and Vascular Biology. 37:1860-1868
10. S-亚硝基化谷胱甘肽还原酶抑制剂在改善肺纤维化血管新生中的应用. 中国. 2022114120535. 20231113. 1